Resistant germs in long-term care and in the home
We are studying the transmission of resistant enterobacteria in long-term care and in the home. Together with the findings from other research groups we aim to provide a comprehensive picture of the ways in which these pathogens spread.
Project description (ongoing research project)
Multi-resistant intestinal microbes of the enterobacteria family are spreading rapidly all across the globe. Switzerland has also seen an increase of new infections. The pathogens can be found in hospitals, homes, on food and in the environment. Working together with research groups from six European countries, we seek to explain the precise ways in which they spread. Within the framework of our subproject, we are investigating how resistance is transferred within long-term care institutions and private homes. We are analysing various strains of enterobacteria, as well as mobile genetic elements that are exchanged between bacteria and play an important role in the formation of resistance.
There has been a general lack of understanding of the ways in which multi-resistant enterobacteria spread. With modern methods of gene analysis this can now be studied in a targeted manner.
Based on the results of the individual subprojects we will produce mathematical models that reveal the ways in which multi-resistant enterobacteria spread, thus making prognoses possible.
Our models will support the work of health authorities in developing suitable measures to prevent the spread of resistant germs.
Understanding and modelling reservoirs, vehicles and transmission of ESBL-producing Enterobacteriaceae in the community and long term care facilities